Designing and synthesis of DPAs ligands to induce structural modification of Riboflavin

One of the most fascinating aspects of enzymes is the way these biological catalysts have been designed in order to be able to carry out highly selective reactions under mild conditions. Controlled modification and artificial tuning of Nature’s legacy, using molecular biology technices together with new chemical methods in the field o f bioorganic syntheses, led chemists to investigate access to modified proteins, going as far as designing artificial enzymes.